Top 10 Deadliest Diseases

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One of the most tragic parts of being human is being afflicted by diseases with high morbidity and mortality. Here is our list of top 10 deadliest diseases ever known to man.


1. AIDS; 25 million from 1981 to present

AIDS is a mix of infections and complications as a result of progressive damage to the body’s immune system caused by HIV. AIDS is now considered a pandemic.


2. Influenza; 36,000 deaths annually

Influenza, which is more commonly known as flu, is a highly infectious disease that is caused by influenza virus. Transmission of the disease is by airborne and through physical contact.


3. Spanish Flu, 1918-19; 100 million deaths

The flu pandemic that happened in 1918 is termed as a category 5 flu pandemic which was caused by the flu virus strain A with subtype H1N1.


4. Bubonic Plague; 250 million deaths

This disease outbreak was mainly caused by fleas and rodents infected with Xenopsylla cheopsis. Humans were infected after being bitten by an affected rodent.


5. Malaria; 2.7 million deaths annually

Malaria is an infectious disease which is vector-borne. The causative agent is the protozoan parasites. It is a common disease in the sub-tropics and tropical regions.

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