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Posted on 02 July 2009.
Hybrids by their very nature are highly fuel efficient vehicles, hence there is a preponderance of them in this list. The average mileage is calculated from equal portions of city and highway driving.
1. Toyota Prius
Estimated 46 mpg – The most popular hybrid of the lot, it has a great hatchback body and a Buck Rogers interior. Practical and roomy, it offers a lot of amenities and enough space for a family of five. Only slightly higher in price than a mid-size sedan, it offers the best fuel economy of all vehicles.
2. Honda Civic Hybrid
Estimated 42 mpg – This hybrid combines Honda Civic’s style and functionality with amazing fuel economy. Priced fairly higher than a normal Civic, it is a normal 5 seat sedan with electric motors, combined with much needed savings on gasoline.
3. Smart fortwo
Eestimated 36 mpg – A rear-engine two-seater car, Smart fortwo is an inexpensive car, small enough for two and even comes in a convertible model. A great way to save fuel and money. Fortwo is the most fuel-efficient vehicle in the two-seater class.
4. Nissan Altima Hybrid
Estimated 30 mpg (manual), 29 mpg (automatic) – A mid-size sedan, it is more sportier than most hybrids, and yet has the heart of a big car. Among mid-size cars it is the best option for those who are looking to save fuel, and yet have a car large enough for a small family.
5.Toyota Camry Hybrid
Estimated 34 mpg – Camry lovers will love this new version, cause it combines the beauty and styling of the original Camry with fuel economy and money saving. It has a larger engine than the Prius , ordinary tires and a familiar shape. But it gives 35% more on a gallon of gas.

Look out side of the USA and you will see diesels that will smash every car on this list.