While technology and new inventions in the field of medicine has been marvelously moving ahead, there are still certain diseases that do not consist of a cure at all. In addition, most of the diseases turn out to be as deadly as anything else, which can erase the entire human race when not handled with care.
Pandemic diseases are the diseases that spread wide over an entire geographical area and killing thousands of innocent people on the go. There are some most deadly diseases that are listed below. Learning about them is really important since we should be aware of what has to be taken serious and also to understand that nature always has the upper hand and can destroy us in no time.

1.    Salmonella as well as E.coli:

This disease is food borne. In fact, most of them enter our body system through the animals that we feed on. The current scenario holds that people who breed these animals tend to give them strong medicines irrespective of their health condition. This is the reason why our immune system seems to become less reactive to the antibiotics that we receive later on.

2.    Yellow Fever Viruses:

Aedes mosquito is responsible for this sort of a disease. It will soon take effect and move quicker than you can imagine. This is nothing but the deadly malaria. Though it seems to have been held under control, caution should definitely be exercised.

3.    SARS:

This virulent virus was one of the deadliest airborne diseases so far. In fact, the number of lives claimed by it is also huge. This disease is caused by corona viruses. This infection hit the world in the year 2003.

4.    Ebola Liver Infection:

This is nothing but the hemorrhagic fever that is deadly and also a quick destroyer. This causes the patient to excessively bleed internally and then finally approach death. This causes the capillary walls to cut and start bleeding. Hence, it is really very dangerous.

5.    MRSA:

This is a mutant variant that causes something similar to the staph infection that is so commonly seen in hospitals and nursing homes. It cannot be treated with any kind of antibiotic. Hence, it can turn out to be a vicious killer. It is a common disease in places where close contact exists. Some of the most commonly infected areas are schools, offices, shopping malls, etc.

6.    Dengue:

Nothing can get worse than the mosquito bite. Mosquitoes have been found to infect human beings with several diseases directly into the blood. Dengue fever is also like the yellow fever but the severity is more compared to it. It generally tends to appear as large outbreaks.

7.    Foot and Mouth Disease:

This is a common disease among infants and children of certain age. The viruses causing this disease are benign. The children who get infected with it get some kind of spots all around the mouth and develop fever. It will last up to several weeks.

8.    Bird Flu or Avian Flu:

This kind of flu spreads from a bird to a human being and it still has not learned moving from human to human. Nevertheless, the fever when untreated can be a life threat to the patient.

9.    Swine Flu:

This epidemic is the most deadliest that humans have ever seen. In fact, it is highly mobile and can be transferred from one person to the other. Severity in this includes respiratory disorders and ultimate death in the worst cases.

10.    Cholera:

This is also an epidemic that spreads easily from person to person. It is caused by a virus called as vibrio cholerae. A person suffering from it can die within a matter of hours.

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Have you ever been scared by the idea of death? If the answer is negative then you may like to think again. Here is a list of top ten most hazardous diseases of the developing world which can affect any one if one doesn’t take enough precautions attached with them. These diseases have been ranked by their annual death toll which is updated annually. The list is as follows:

1. Respiratory Infections
Mostly these lower respiratory infections include pneumonia and  diseases of the lungs, tracheal tube etc. These diseases often spread by coughing, sneezing, laughing or exhaling. These diseases have an annual death toll of more than four million people.

2. HIV/AIDS
“Human immunodeficiency virus” also known as HIV, destroys the immune system of human body. It can spread by unprotected sex, unsafe blood transfusions or contaminated needles and from even mother to child during child birth. The death toll of this deadly disease stands at more than 3 million deaths annually

3. Malaria
Malaria is spread by mosquito bites and usually turns fatal if proper treatment is not meted out to the patient. The death toll for this disease stands between one million and five million annually and the number of people affected by it in the world stands around 300 million. The best prevention to this disease is the use insecticide-treated mosquito nets and spraying of indoor insecticide.

4. Diarrhoea
Diarrhoea is caused by cholera or dysentery and is a result of infection from bacteria and microscopic worms. Dehydration is the most common cause of death in deaths related with diarrhoea. The death toll for this disease stands at around two million deaths annually. Contaminated food or water usually leads to being infected by diarrhoea.

5. Tuberculosis
Tuberculosis or “TB” as it is commonly known is spread by coughing or sneezing and its common symptoms are weight loss, weakness and common chills. The annual death toll stands at two million. It’s most common treatment is DOTS (Directly Observed Therapy Short Course).

6. Measles
Measles is usually caused by coughing and sneezing as it is highly contagious and can cause damage to brain or blindness and can lead to death if proper medical treatment is not administered. The death toll stands at half million cases per year. Successful vaccination has been developed to fight this scourge and can be treated with drugs.

7. Whooping Cough
It is caused by coughing, sneezing or talking. It’s a highly communicable disease caused by bacterial infection in respiratory tract and the annual death toll stands between two to three million cases per year. It can be treated by antibiotics and vaccines.

8. Tetanus
Its also known as lockjaw. Tetanus is a disease caused in our central nervous system due to an untreated wound getting infected by bacteria. Annual death toll stands at around two million cases per year. This disease can be prevented by vaccines.

9. Meningitis
It is a highly fatal infectious disease that affects the brain and is caused by close contact or sharing of utensils. The annual death toll stands at around two million. It can be prevented by vaccines and antibiotics including penicillin but often five to ten percent patients die even after treatment.

10. Syphilis
It is caused by unprotected sexual intimacy and can even be passed by a mother to her child during birth. Many common antibiotics do not work against this disease and the annual death toll stands at one and a half million.

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Modern medicine had seen dramatic advancement at controlling various diseases affecting man. Nonetheless, there still remains an assortment of diseases that has no cure. Let us take a look at the list of top 10 incurable diseases that afflict many people every year.

1. Common Cold – The common is a viral infection that is defined as an acute type of ailment that initially affects the upper respiratory tract. In the more advanced cases, the infection reaches the lower portion and can cause secondary infections that affect the middle ears and the eyes.

2. Cancer – This incurable disease has more than 100 distinct forms which is generally defined by the uncontrolled growth of abnormal and invasive cells in the body.

3. Asthma – Asthma is a chronic disease affecting the lungs. It generally leads to the inflammation of airways and causes shortness of breath, coughing and wheezing.

4. AIDS/HIV – AIDS is a contagious disease that affects the immune system. HIV is the pathogen that causes AIDS. An individual that is afflicted by AIDS are prone to a wide variety of malignancies and infections.

5. Diabetes Type 2 – This incurable disease impairs the metabolism of carbohydrates resulting to the inability of the body to produce insulin and maintain the normal level of blood sugar.

6. Creutzfeldt – Jakob disease – This incurable and very rare disease is a highly degenerative ailment that attacks the central nervous system. The probability occurrence of this disease is placed at one in a million individuals.

7. Influenza – This incurable ailment is more commonly known as flu. There are three major types of flu designated as type A, type B and type C.

8. Lupus Erythematosus – This incurable disease is more commonly referred to as lupus. It is an autoimmune disease that results to inflammation in specific parts of the body.

9. Polio – This type of incurable disease is sometimes referred to as infantile paralysis. It is a highly infectious disease that attacks the nervous system which can lead to paralysis when not properly managed.

10. Ebola – This viral disease causes severe and extremely serious hemorrhagic fever which oftentimes results to death. It is zoonotic and also affects chimpanzees and gorillas.

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One of the most tragic parts of being human is being afflicted by diseases with high morbidity and mortality. Here is our list of top 10 deadliest diseases ever known to man.

1.    AIDS; 25 million from 1981 to present
AIDS is a mix of infections and complications as a result of progressive damage to the body’s immune system caused by HIV. AIDS is now considered a pandemic.

2.    Influenza; 36,000 deaths annually
Influenza, which is more commonly known as flu, is a highly infectious disease that is caused by influenza virus. Transmission of the disease is by airborne and through physical contact.

3.    Spanish Flu, 1918-19; 100 million deaths
The flu pandemic that happened in 1918 is termed as a category 5 flu pandemic which was caused by the flu virus strain A with subtype H1N1.

4.    Bubonic Plague; 250 million deaths
This disease outbreak was mainly caused by fleas and rodents infected with Xenopsylla cheopsis. Humans were infected after being bitten by an affected rodent.

5.    Malaria; 2.7 million deaths annually
Malaria is an infectious disease which is vector-borne. The causative agent is the protozoan parasites. It is a common disease in the sub-tropics and tropical regions.

6.    Ebola; 160,000 deaths from 2000 to present
The Ebola virus was first isolated in1976 from the dual outbreaks that occurred in Zaire and Sudan. It is a zoonotic disease as it affects lowland apes as well as humans.

7.    Cholera; 12,000 deaths from 1991 to present
The epidemic or Asiatic cholera is a very serious type of diarrheal ailment caused by Vibrio cholera. The mode of transmission is by ingesting contaminated food and water.

8.    Smallpox; Population drop from 12 million to 235,000
Smallpox is a highly contagious viral disease that has two variants. The V major has a 35% mortality rate while the less severe V minor has a 1% mortality rate.

9.    Polio, 10,000 deaths from 1916 to present
Polio or infantile paralysis is a viral disease that is transmitted through the fecal-oral course.

10. Black Death; 75 million deaths
The Black Plague is the one of the most serious pandemic outbreak in modern history. It was believed to have started in Central Asia and affected Europe during the 13th century.

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